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KMID : 1034720170090010001
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Journal of Neurosonology and Neuroimaging
2017 Volume.9 No. 1 p.1 ~ p.6
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Standardized Transcranial Doppler Protocol for Clinical Study
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Kim Kwang-Hyun
Yoon Hye-Rin
Han Sang-Won
Roh Sook-Young
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Abstract
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Transcranial Doppler (TCD) is a physiological ultrasound test with established safety and efficacy. In recent years, TCD has become a general practice in the diagnostic and monitoring study of cerebral hemodynamics. The noninvasiveness, convenience, and repeatability of TCD examination could promote its clinical and research applications will continue to increase in many brain diseases. It is also the most convenient way to monitor vascular changes in response to therapeutic interventions. However, it is highly operator dependent with the handheld technique requiring detailed three-dimensional knowledge of cerebrovascular anatomy and experience for accurate interpretation. Therefore, a standardized protocol, based on accepted TCD practice, is essential for the clinical study using TCD. Standardized scanning protocol with transducer positioning and orientation, depth selection and vessel identification will support TCD research applications. This article aims to provide an overview of a few clinical TCD studies and introduce standardized TCD protocols. A brief outline is provided of its role and limitations in its diverse applications.
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KEYWORD
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Doppler Transcranial Sonography, Stroke, Practical Clinical Trials
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